Symbol Name ID |
Il7r
interleukin 7 receptor MGI:96562 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | immune system phenotype |
increased thymocyte apoptosis |
abnormal T cell proliferation |
decreased T cell proliferation |
small thymus |
thymus hypoplasia |
decreased thymocyte number |
increased thymocyte number |
abnormal B cell differentiation |
decreased immature B cell number |
arrested B cell differentiation |
abnormal T cell differentiation |
abnormal CD4-positive T cell differentiation |
abnormal CD8-positive, alpha-beta T cell differentiation |
increased double-negative T cell number |
decreased double-positive T cell number |
increased double-positive T cell number |
abnormal gamma-delta T cell differentiation |
arrested T cell differentiation |
decreased mature B cell number |
decreased B-1 B cell number |
decreased B cell number |
increased B cell number |
abnormal T cell subpopulation ratio |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased NK T cell number |
absent mature gamma-delta T cells |
increased gamma-delta T cell number |
decreased memory T cell number |
decreased T cell number |
decreased lymphocyte cell number |
decreased leukocyte cell number |
abnormal T cell morphology |
spleen hypoplasia |
abnormal CD4-positive, alpha-beta T cell physiology |
absent Peyer's patches |
lymph node hypoplasia |
|
Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||
Il7rtm1Abra/Il7rtm1Abra | |||||||||||||||||||||||||||||||||||||||
Il7rtm1Iku/Il7rtm1Iku | * | ||||||||||||||||||||||||||||||||||||||
Il7rtm1Imx/Il7rtm1Imx | |||||||||||||||||||||||||||||||||||||||
Il7rtm1Imx/Il7rtm1Imx Tg(Lck-Il7r)1676Trma/? |
|||||||||||||||||||||||||||||||||||||||
Il7rtm2Iku/Il7rtm2Iku Tg(Cd4-cre)1Cwi/? (conditional) |
|||||||||||||||||||||||||||||||||||||||
Il7rtm1.1Asin/Il7rtm1Imx Tg(Cd4-cre)1Cwi/0 (conditional) |
|||||||||||||||||||||||||||||||||||||||
Il7rtm1.1Asin/Il7rtm1Imx Tg(Cd8a*-cre)B8Asin/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/30/2024 MGI 6.23 |
|
|